- A nutritional and herbal formulation with sedative properties to promote sleep
- Provides 300 mg of magnesium per serve
- Contains a unique and specific blend of three Magnesium salts for optimal sleep support
- Each 7g serve contains 3.9gm of glycine
- Utilises affron®, a standardised extract of Saffron, clinically studied in subjects reporting poor sleep
- Includes Passionflower and California poppy
- Delicious Natural Lemon Lemonade Flavour
Magnesium is one of the most ubiquitous and essential minerals in the body. It is a critical nutrient in almost every cellular metabolic and biological process, with enzyme databases listing over 600 enzymes that use magnesium as a co-factor and a further 200 being directly activated by magnesium. As a natural calcium channel blocker, muscle relaxant, facilitator of calming effects upon the nervous system, and a required element for electrolyte balance and proper functioning of sodium-potassium ATPase pumps, magnesium plays a crucial role in supporting, muscle contraction and relaxation, neurological health, neurotransmission and psychological balance.
Skeletal muscle & nervous system function
Magnesium is a critical regulator of the activity rate of the Sodium-Potassium ATPase pump (Na+, K+- ATPase pump), which is required for the removal of sodium from inside the cell in exchange for potassium. This makes Magnesium vital for maintaining the electrical potential of skeletal muscles and nerves and for neurotransmission across neuromuscular junctions. As well as moderating the function and activity of the Na+, K+- ATPase pump, subsequently affecting both contraction and relaxation phases of muscle movement, magnesium also contributes to skeletal muscle function by facilitating oxygen utilisation, ATP production and electrolyte balance. In the nervous system, Magnesium is vital for neurotransmitter binding and subsequent transmission. Magnesium can cross the blood-brain barrier and acts as a calcium antagonist at neuromuscular junctions, affecting NMDA receptors. It also agonises GABA receptors, thereby having an overall calming effect on the nervous system. Magnesium absorption is seen as a challenge as various factors such as solubility, gastric pH, the formation of a hydration shell, and transport can influence magnesium bioavailability. Organic forms such as citrates, amino acid chelates, glycinates, aspartates and glycerophosphates tend to have the most optimal bioavailability profiles.
Saffron is a herb that has been used for thousands of years for its effects on inflammation and the nervous system. Saffron contains three main constituents that show the most biological activity, and they are known collectively as “lepticrosalides”. They include crocin, picrocrocin and safranal. Modern investigations have confirmed Saffron’s traditional uses, particularly its effects on mood and sleep. The ability of Saffron to improve sleep quality is thought to be brought about by mechanisms relating to its possible influence over melatonin production, improvements in delta powdered sleep phases and non-rapid eye movement sleep Moreover, the general calming effects that Saffron brings to the nervous system may also contribute to its ability to promote a more refreshing sleep Driving Saffron’s effects on emotional well-being and mood balance are its serotonergic, anti-inflammatory, antioxidant, neuro-endocrine (dampens HPA response to stress), neuroprotective and soporific activity. Saffron’s constituents can interact with the cholinergic, glutamatergic and GABA systems whilst increasing cAMP response element binding protein (CREB) and brain-derived neurotropic factor (BDNF) providing neuroprotective effects
Directions to use:-
Adults: mix 7 g (one level scoop) of the Lemon Lemonade powder with 200 mls water and consume immediately. Take 1 hour before bed or as directed by your healthcare practitioner
- No added: Gluten, dairy, soy, or nuts
- Vegan Friendly
- If symptoms persist, seek the advice of a healthcare professional
- Vitamin and/or mineral supplements should not replace a balanced diet.
- Not to be used during pregnancy and/or breastfeeding.
- Contains sulfites and phenylalanine